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Table 2 Blood biochemistry differences (Mean ± SD, n = 7) between the study groups (saline, SMOFlipid and propofol Lipuro) obtained from 12 to the 20 h of drug infusion

From: In vivo study of hepatic oxidative stress and mitochondrial function in rabbits with severe hypotension after propofol prolonged infusion

Parameter Saline SMOFlipid Propofol Lipuro
  12 h sampling
 ALP 144.8 ± 27.0a 315.7 ± 32.6b 198.7 ± 46.6c
 ALT 23,6 ± 9.6a 75.9 ± 25.7b 46.4 ± 15.5c
 AST 20.8 ± 6.4a 68.8 ± 21.5b 38.3 ± 25.1a
 Glucose 106.6 ± 15.1a 135.2 ± 24.4b 124.1 ± 14.5a,b
 Cholesterol 29.0 ± 5.1a 73.1 ± 43.5b 106.6 ± 16.9c
 Triglycerides 55.2 ± 12.8a 922.1 ± 194.3b 768.6 ± 124.7b
 LDH 140.6 ± 33.7a 671.9 ± 358.8b 588.9 ± 285.2b
 CK 1149.5 ± 261.3a 4898.0 ± 214.1b 1278.7 ± 368.8c
 Amylase 302.8 ± 35.6a 374.6 ± 91.4a 449.9 ± 87.9b
 Urea 28.4 ± 8.5a 26.4 ± 4.6a 69.5 ± 18.7b
 Creatinine 0.9 ± 0.7a 1.0 ± 0.3a 2.9 ± 0.4b
 Phosphorus 4.3 ± 1.0a 7.8 ± 3.2b 10.7 ± 3.8b
 Ca2+ 11.7 ± 0.8a,b 12.5 ± 3.5a 9.7 ± 1.2b
 Na+ 129.9 ± 12.1a 145.3 ± 12.3b 140.4 ± 5.9a,b
  15 h sampling
 ALP 148.0 ± 16.1a 255.4 ± 44.1b 171.8 ± 48.7a
 ALT 27.0 ± 8.6a 65.6 ± 34.9b 45.3 ± 13.7a
 AST 25.5 ± 4.8a 42.3 ± 27.1a 88.7 ± 29.1b
 Glucose 105.5 ± 8.9a 134.3 ± 18.1b 126.1 ± 15.7a,b
 Cholesterol 36.6 ± 6.4a 79.8 ± 37.4b 122.5 ± 14.8c
 Triglycerides 61.8 ± 26.8a 1066.7 ± 203.1b 1022.7 ± 94.2b
 LDH 142.8 ± 39.4a 730.3 ± 366.2b 587.7 ± 181.1b
 CK 1122.8 ± 172.8a 7225.4 ± 863.7b 1840.0 ± 390.7c
 Amylase 326.6 ± 51.1a 371.6 ± 88.2a 459.9 ± 101.6b
 Urea 25.5 ± 7.1a 28.7 ± 7.1a 82.2 ± 13.3b
 Creatinine 1.2 ± 0.4a 1.3 ± 0.3a 3.4 ± 0.5b
 Phosphorus 4.2 ± 0.8a 8.6 ± 2.8b 11.8 ± 5.5c
 Ca2+ 11.8 ± 0.7a 1.4 ± 2.5a 9.7 ± 2.1a
 Na+ 139.2 ± 10.2a 144.2 ± 4.4a 140.6 ± 7.8a
  18 h sampling
 ALP 132.2 ± 21.8a 260.1 ± 49.8b 173.8 ± 44.2a
 ALT 23.0 ± 12.9a 58.4 ± 22.1b 56.1 ± 15.8a
 AST 19 ± 4.7a 33.0 ± 18.5a 100.4 ± 18.6b
 Glucose 101.8 ± 12.2a 120.4 ± 26.1a 127.6 ± 20.8a
 Cholesterol 30.7 ± 6.2a 82.1 ± 58.5b 131.3 ± 27.8c
 Triglycerides 73.6 ± 26.9a 1608.5 ± 226.2b 1119.6 ± 112.3c
 LDH 158.5 ± 51.2a 879.6 ± 373.7b 602.5 ± 331.4c
 CK 1113.4 ± 468.6a 6584.5 ± 542.1b 2063.1 ± 495.5c
 Amylase 369.5 ± 32.1a 586.2 ± 101.4b 513.7 ± 138.2b
 Urea 26.4 ± 6.4a 18.9 ± 3.3a 95.3 ± 10.0b
 Creatinine 0.9 ± 0.6a 1.2 ± 0.4a 3.7 ± 0.4b
 Phosphorus 3.9 ± 0.6a 9.1 ± 3.2b 11.9 ± 7.4b
 Ca2+ 12.1 ± 1.9a 11.1 ± 3.1a 9.6 ± 1.9a
 Na+ 139.6 ± 9.5a 143.3 ± 9.5a 139.2 ± 6.9a
  20 h sampling
 ALP 135.8 ± 16.4a 273.8 ± 47.2b 189 ± 52.7c
 ALT 25,3 ± 11.4a 73.6 ± 26.2b 48.0 ± 18.0c
 AST 29.2 ± 13.2a 47.6 ± 17.4a 140.0 ± 24.2b
 Glucose 99.8 ± 13.1a 147.6 ± 17.9b 125.8 ± 14.3a,b
 Cholesterol 30.2 ± 7.6a 87.6 ± 57.4b 138.7 ± 48.9c
 Triglycerides 66.1 ± 15.8a 1685.4 ± 103.4b 1086.8 ± 254.1c
 LDH 155.2 ± 56.7a 750.0 ± 256.2b 607.0 ± 272.4b
 CK 1035.8 ± 385.2a 10,492.0 ± 874.3b 3988.8 ± 657.6c
 Amylase 336.2 ± 27.9a 668.9 ± 112.4b 502.7 ± 112.3c
 Urea 26.7 ± 4.2a 23.2 ± 5.5a 89.7 ± 15.2b
 Creatinine 1.03 ± 0.4a 1.1 ± 0.3a 3.9 ± 0.7b
 Phosphorus 4.3 ± 0.9a 9.7 ± 4.6b 12.4 ± 3.1b
 Ca2+ 11.7 ± 1.7a 12.4 ± 4.0a 9.9 ± 2.6a
 Na+ 130.5 ± 14.2a 137.5 ± 5.4a 139.4 ± 5.8a
  1. Different letters show significant differences between study groups (p < 0.05)