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Table 4 Crude- and adjusted odds ratios (OR) for impaired HRQoL assessed by EQ-5D index value and EQ-VAS

From: Health-related quality of life after deep vein thrombosis

Variable EQ-5D index value EQ-VAS
N = 254 Crude OR (95 % CI) p value# Adjusted ORa (95 % CI) p value# adjusted N = 250 Crude OR (95 % CI) p value# Adjusted ORa (95 % CI) p value# adjusted
Female 87 2.7 (1.3–5.3) 0.05    86 1.3 (0.6–2.8) 0.5   
Age (continuous variable) 254 1.0 (1.0–1.0) 0.4    250 1.0 (1.0–1.1) 0.03 1.0 (1.0–1.0) 0.5
Time from diagnosis to examination (continuous variable) 254 1.1 (1.0–1.3) 0.2    250 1.0 (0.8–1.1) 0.7   
Unemployed 135 2.5 (1.3–4.9) 0.006 2.3 (1.1–4.8) 0.03 135 4.2 (2.1–8.4) <0.001 4.3 (2.0–9.0) <0.001
BMI > 30.0 kg/m2 76 3.1 (1.7–5.7) <0.001 2.3 (1.1–4.2) 0.005 75 3.3 (1.8–6.1) 0.003 2.5 (1.3–5.0) 0.008
Current or previous daily smoking 131 1.2 (0.7–2.2) 0.5    127 1.2 (0.7–2.2)    
Still on anticoagulation 74 0.8 (0.4–1.5) 0.4    72 1.2 (0.6–2.3) 0.6   
No ECS after DVT 21 1.1 (0.3–3.4) 0.9    18 0.7 (0.2–2.4) 0.6   
COPD 13 1.6 (0.5–5.7) 0.4    12 1.7 (0.5–6.0) 0.4   
Heart failure 12 1.2 (0.3–4.8) 0.7    12 3.7 (1.1–11.9) 0.03   
Current or previous cancer 24 1.3 (0.5–3.4) 0.6    24 2.3 (0.9–5.4) 0.08   
Proximal DVTb 161 0.8 (0.4–1.6) 0.6    159 0.9 (0.5–1.8) 0.8   
PTS 121 13.9 (5.7–34.1) <0.001 11.0 (4.6–29.7) <0.001 120 5.9 (2.9–11.9) <0.001 4.8 (2.3–10.0) <0.001
Multiple DVTs 79 1.4 (0.8–2.7) 0.3    71 1.4 (0.7–2.6) 0.3   
Provoked DVT 119 0.8 (0.4–1.5) 0.5    116 1 (0.5–1.7) 0.9   
  1. DVT deep vein thrombosis, ECS elastic compression stockings, BMI body mass index, PTS post thrombotic syndrome, COPD chronic pulmonary obstructive disease, Impaired HRQoL EQ-5D index value <25th percentile in patient group (0.72) and EQ VAS value <25th percentile in patient group (60)
  2. #Wald test
  3. aAdjusted for all other significant variables in the multivariate model
  4. bIn or above popliteal vein