Health-related quality of life after deep vein thrombosis

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Table 4 Crude- and adjusted odds ratios (OR) for impaired HRQoL assessed by EQ-5D index value and EQ-VAS

Variable	EQ-5D index value					EQ-VAS
Variable	N = 254	Crude OR (95 % CI)	p value^#	Adjusted OR^a (95 % CI)	p value^# adjusted	N = 250	Crude OR (95 % CI)	p value^#	Adjusted OR^a (95 % CI)	p value^# adjusted
Female	87	2.7 (1.3–5.3)	0.05			86	1.3 (0.6–2.8)	0.5
Age (continuous variable)	254	1.0 (1.0–1.0)	0.4			250	1.0 (1.0–1.1)	0.03	1.0 (1.0–1.0)	0.5
Time from diagnosis to examination (continuous variable)	254	1.1 (1.0–1.3)	0.2			250	1.0 (0.8–1.1)	0.7
Unemployed	135	2.5 (1.3–4.9)	0.006	2.3 (1.1–4.8)	0.03	135	4.2 (2.1–8.4)	<0.001	4.3 (2.0–9.0)	<0.001
BMI > 30.0 kg/m²	76	3.1 (1.7–5.7)	<0.001	2.3 (1.1–4.2)	0.005	75	3.3 (1.8–6.1)	0.003	2.5 (1.3–5.0)	0.008
Current or previous daily smoking	131	1.2 (0.7–2.2)	0.5			127	1.2 (0.7–2.2)
Still on anticoagulation	74	0.8 (0.4–1.5)	0.4			72	1.2 (0.6–2.3)	0.6
No ECS after DVT	21	1.1 (0.3–3.4)	0.9			18	0.7 (0.2–2.4)	0.6
COPD	13	1.6 (0.5–5.7)	0.4			12	1.7 (0.5–6.0)	0.4
Heart failure	12	1.2 (0.3–4.8)	0.7			12	3.7 (1.1–11.9)	0.03
Current or previous cancer	24	1.3 (0.5–3.4)	0.6			24	2.3 (0.9–5.4)	0.08
Proximal DVT^b	161	0.8 (0.4–1.6)	0.6			159	0.9 (0.5–1.8)	0.8
PTS	121	13.9 (5.7–34.1)	<0.001	11.0 (4.6–29.7)	<0.001	120	5.9 (2.9–11.9)	<0.001	4.8 (2.3–10.0)	<0.001
Multiple DVTs	79	1.4 (0.8–2.7)	0.3			71	1.4 (0.7–2.6)	0.3
Provoked DVT	119	0.8 (0.4–1.5)	0.5			116	1 (0.5–1.7)	0.9

DVT deep vein thrombosis, ECS elastic compression stockings, BMI body mass index, PTS post thrombotic syndrome, COPD chronic pulmonary obstructive disease, Impaired HRQoL EQ-5D index value <25th percentile in patient group (0.72) and EQ VAS value <25th percentile in patient group (60)
^#Wald test
^aAdjusted for all other significant variables in the multivariate model
^bIn or above popliteal vein