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Table 2 IC50 values obtained for methanolic and dichloromethane extracts (µg extract/ml) that presented the highest anti-proliferative activity on HepG-2 cells

From: High cytotoxicity and anti-proliferative activity of algae extracts on an in vitro model of human hepatocellular carcinoma

Algae

Extract

Methanol

IC50 (µg/ml)

Dichloromethane

IC50 (µg/ml)

Fucus spiralis

1039.0 (603.7–1789.0)

–

Asparagopsis armata

857.3 (524.5–1401.0)

518.9 (341.3–789.0)

Plocamium cartilagineum

–

852.7 (471.9–1541.0)

Sphaerococcus coronopifolius

646.5 (398.4–1049.0)

32.3 (22.4–46.7)

  1. Values are expressed as means with 95 % confidence intervals. Cisplatin and tamoxifen were used as standard drugs. Cisplatin and tamoxifen exhibited an IC50 of 22.63 µg/ml (18.24–28.07) and 16.97 µg/ml (11.83–24.35), respectively