Table 1 Clinicopathological characteristics of patient with stage IA2/IB1/IIA1 cervical squamous cell cancer (n = 276) in relation to the pelvic lymph node status
Characteristics | Total | Positive lymph node metastasis n (%) | Negative lymph node metastasis n (%) | p-value |
|---|---|---|---|---|
54 | 222 | |||
Age, years | ||||
<40 | 45 | 8 (14.8) | 37 (16.7) | 0.947 |
≥40 | 231 | 46 (85.2) | 185 (83.3) | |
Menopausal status | ||||
Premenopausal | 158 | 26 (48.1) | 132 (59.5) | 0.321 |
Postmenopausal | 118 | 28 (51.9) | 90 (40.5) | |
FIGO stage | ||||
IA2/IB1 | 215 | 36 (66.7) | 179 (80.7) | 0.085 |
IIA1 | 61 | 18 (33.3) | 43 (19.4) | |
HPV infection status | ||||
Negative | 20 | 1 (2.0) | 19 (9.5) | 0.180 |
Positive | 232 | 50 (98.0) | 182 (90.5) | |
SCCAg (μg/L) | ||||
≤1.5 | 198 | 24 (46.1) | 174 (81.3) | <0.001 |
>1.5 | 68 | 28 (53.9) | 40 (18.7) | |
Histological grade | ||||
Well differentiated | 4 | 0 (0) | 4 (1.8) | 0.733 |
Moderately differentiated | 163 | 34 (63.0) | 129 (58.1) | |
Poorly differentiated | 109 | 20 (37.0) | 89 (40.1) | |
Tumor size (cm) | ||||
≤2 | 124 | 8 (14.8) | 116 (52.3) | <0.001 |
>2 | 152 | 46 (85.2) | 106 (47.7) | |
Tumor size(cm) | ||||
≤3 | 225 | 32 (59.3) | 193 (86.9) | <0.001 |
>3 | 51 | 22 (40.7) | 29 (13.1) | |
Depth of stromal invasion | ||||
Superficial | 129 | 6 (11.1) | 122 (55.0) | <0.001 |
Middle | 69 | 16 (29.6) | 53 (23.9) | |
Deep-full | 79 | 32 (59.3) | 47 (21.1) | |
Lymphovascular invasion | ||||
Negative | 147 | 14 (25.9) | 133 (59.9) | <0.001 |
Positive | 129 | 40 (74.1) | 89 (40.1) | |