Fig. 4

Intratracheal administration of Mycobacterium into the lungs of wild-type (WT) and SPC-CCL1 transgenic (Tg) mice. To produce a model of chronic lung inflammation, mice were intratracheally administered Bacille de Calmette et Guérin (BCG). a Representative lung image of WT mice, 28 days after administration. b Representative lung image of SPC-CCL1 Tg mice, 28 days after administration. Enhanced granuloma formation was observed in the lungs of Tg mice, compared to WT mice c. *P value <0.05 compared to WT mice