Table 2 Baseline Characteristics of cohort stratified by azithromycin use
Factor | Group | Treatment | P value | |
|---|---|---|---|---|
No-AZM | AZM | |||
N | 96 | 29 | ||
Age (years) | 76.5 [67, 82.25] | 70 [65, 81] | 0.35 | |
Sex | M/F | 66 (68.8)/30 (31.2) | 19 (65.5)/10 (34.5) | 0.821 |
Cirrhosis | Yes | 10 (10.4) | 3 (10.3) | 1 |
Sepsis | pulmonary | 55 (57.3) | 23 (79.3) | 0.048 |
Nonpulmonary | 41 (42.7) | 6 (20.7) | ||
APACHE.II | 23 [18, 26] | 24 [21, 27] | 0.462 | |
McCabe | 1/2/3 | 88 (91.7)/3 (3.1)/5 (5.2) | 26 (89.7)/2 (6.9)/1 (3.4) | 0.63 |
ARDS severity | Mild | 5 (5.2) | 5 (17.2) | 0.113 |
Moderate | 45 (46.9) | 13 (44.8) | ||
Severe | 46 (47.9) | 11 (37.9) | ||
SOFA | 7 [5, 11] | 9 [7, 12] | 0.143 | |
PaO2/FiO2 | 100.45 [70.97, 132.70] | 114.20 [84.50, 180.00] | 0.045 | |
CT.score | 214.05 [184.80, 265.60] | 211.70 [188.10, 268.50] | 0.667 | |
Alb, g/dL | 2.90 [2.58, 3.30] | 2.50 [2.20, 3.00] | 0.002 | |
WBC | 10,450 [5250, 14,400] | 7300 [2300, 12,200] | 0.055 | |
C-reactive protein, mg/dL | 15.33 [8.68, 25.07] | 19.69 [10.22, 30.10] | 0.239 | |
Lactate dehydrogenase, IU/L | 312 [248.25, 436.50] | 301 [233.00, 434.00] | 0.621 | |
DIC score | 2 [2, 4] | 4 [2, 5] | 0.028 | |
FDP, mg/L | 11.00 [6.72, 18.10] | 11.90 [9.30, 20.00] | 0.382 | |
AntithrombinIII, % | 66.50 [52.75, 81.25] | 65.00 [51.00, 79.00] | 0.527 | |
PLT,X104 | 18.35 [11.93, 28.30] | 12.40 [7.70, 18.40] | 0.003 | |
D.dimer.μg/ml | 5.95 [2.48, 11.00] | 4.60 [3.10, 9.30] | 0.398 | |
Death (%) | 48 (50.0) | 10 (34.5) | 0.202 | |