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Table 2 Summary of study characteristics

From: Cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) in symptomatic cervical degenerative disc diseases (CDDDs): an updated meta-analysis of prospective randomized controlled trials (RCTs)

Studies Design Prostheses Country Center No (CDA/ACDF) Age(CDA/ACDF) Male % (CDA/ACDF) Follow up (%)
Zhang et al. (2012) RCT Bryan (Medtronic Sofamor Danek, Memphis, TN, USA) China Multicenter 120
60/60
44.8/45.6 58.3/53.3 NA
Sasso et al. (2007, 2008, 2011), Heller et al. (2009), Riew et al. (2008) RCT Bryan (Medtronic Sofamor Danek, Memphis, TN, USA) USA Multicenter 463
242/221
44.4/44.7 45.5/55.1 73
  RCT Bryan (Medtronic Sofamor Danek, Memphis, TN, USA) USA Multicenter 199
106/93
44.5/44.4 17.0/16.1 NA
Cheng et al. (2009, 2011) RCT Bryan (Medtronic Sofamor Danek, Memphis, TN, USA) USA Singlecenter 83
41/42
47.2/47.7 51.2/54.8 98
Skeppholm et al. (2015) RCT Discover (DePuy Spine, Raynham, MA, USA) Sweden Multicenter 153
73/80
42.2/41.7 49.4//47.1 91
Rozankovic et al. (2014) RCT Discover (DePuy Spine, Raynham, MA, USA) Croatia Singlecenter 101
51/50
41/41 49.0/50.0 100
Qizhi et al. (2014) RCT Discover (DePuy Spine, Raynham, MA, USA) China Singlecenter 30
14/16
47/48 64.2/68.8 100
Coric et al. (2011) RCT Kineflex (Spinal Motion Inc, Mountain View, CA, USA) USA Multicenter 269
136/133
43.7/43.9 37.5/44/4 87
Zhang et al. (2014) RCT Mobi-C (LDR Medical, Troyes, France) USA Multicenter 111
55/56
44.8/46.7 45.5/46.4 NA
Hisey et al. (2014, 2015) RCT Mobi-C (LDR Medical, Troyes, France) USA Multicenter 245
164/81
43/44 47.6/44.4 75
Davis et al. (2013, 2015) RCT Mobi-C (LDR Medical, Troyes, France) USA Multicenter 330
225/105
45.3/46.2 50.2/42.9 86
Phillips et al. (2013, 2015) RCT PCM (NuVasive Inc, San Diego, CA, USA) USA Multicenter 293
163/130
45.3/43.7 52.8/51.9 72.70
McAfee et al. (2010) RCT PCM (NuVasive Inc, San Diego, CA, USA) USA Multicenter 251
151/100
45/44 50.3/47.0 NA
Riina et al. (2008) RCT Prestige ST (Medtronic Sofamor Danek, Memphis, TN, USA) USA Singlecenter 19
10.0/9.0
40.8/38.1 20.0/33.3 84.20
Riew et al. (2008) RCT Prestige ST (Medtronic Sofamor Danek, Memphis, TN, USA) USA Multicenter 111
59/52
43.4/46.0 49.2/40.4 NA
Porchet and Metcalf (2004) RCT Prestige II (Medtronic Sofamor Danek, Memphis, TN, USA) Switzerland Multicenter 55
27/28
44.3/43.2 63.0/40.4 67.3
Mummaneni et al. (2007), Burkus et al. (2010, 2014) RCT Prestige ST (Medtronic Sofamor Danek, Memphis, TN, USA) USA Multicenter 541
276/265
43.3/43/9 46.4/46 77.80
Nabhan et al. (2007a, b, c, 2011) RCT ProDisc-C (Synthes Inc, West Chester, PA,USA) Germany Singlecenter 41
20/21
44 23/18 NA
Murrey et al. (2008, 2009), Delamarter et al. (2010), Kelly et al. (2011), Kesman et al. (2012), Zigler et al. (2013), Delamarter and Zigler (2013) RCT ProDisc-C (Synthes Inc, West Chester, PA,USA) USA Multicenter 209
103/106
42.1/43/5 44.7/46.2 95.20
Vaccaro et al. (2013) RCT SECURE-C (Globus Medical, Audubon, PA, USA) USA Multicenter 380
236/144
43.4/44.4 53.6/48.6 87.10
  1. CDA cervical disc arthroplasty, ACDF anterior cervical discectomy and fusion, RCT randomized controlled trial, NA no available