Table 2 Characteristics of individual studies of GNAS mutation in patients with IPMN
Study | Country | Ethnicity | Detection method | Specimen | GNAS mutation (%) |
|---|---|---|---|---|---|
Amato E | Italy | Caucasian | Sequencing | Tissue | 38/48 (79.2) |
Hosada W | Japan | Asian | Real-time PCR, sequencing | Tissue | 55/91 (60.4) |
Ideno N | Japan | Asian | HRM, sequencing | Tissue | 65/110 (59.1) |
Kanda M | USA | Caucasian | HRM, pyrosequencing | Pancreatic juice | 49/78 (62.8) |
Kuboki Y | Japan | Asian | Sequencing | Tissue | 82/172 (47.7) |
Lee LS | USA | Caucasian | Sequencing | Tissue | 8/19 (42.1) |
Siddiqui AA | USA | Caucasian | Quantitative PCR | Cyst fluid | 4/9 (44.4) |
Singhi AD | USA | Caucasian | Sequencing | Cyst fluid | 18/50 (36.0) |
Takano S | Japan | Asian | Sequencing | Tissue | 4/6 (66.7) |
| Â | Â | Â | Â | Pancreatic juice | 34/82 (41.5) |
Tan MC | USA | Caucasian | Sequencing | Tissue | 23/38 (60.5) |
Wu J | USA | Caucasian | PCR/ligation | Tissue | 36/49 (73.5) |
| Â | Â | Â | Â | Cyst fluid | 51/83 (61.4) |