Table 1 Baseline characteristics of the included studies
Authors (year) | Nation/region | Study design | Study period | NOS | No. Samples | Materials | Investigating fields | Follow-up (maximum) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
Total | PE | NE | CP features | Prognosis | |||||||
Huang et al. (2005) | China | ROS | NI | 7 | 60 | 43 | 17 | Paraffin-embedded tissue | ✓ | ✗ | – |
Liu et al. (2016) | Taiwan | ROS | 2009–2010 | 8 | 22 | 8 | 14 | Paraffin-embedded tissue | ✓ | ✓ | 60 months |
Malusecka et al. (2008) | Poland | ROS | 1993–1995 | 8 | 76 | 59 | 17 | Paraffin-embedded tissue | ✗ | ✓ | 12 months |
Tsai et al. (2014) | Taiwan | ROS | 2004–2010 | 8 | 64 | 39 | 25 | Frozen tissue | ✗ | ✓ | 12 months |
Wang et al. (2011) | China | ROS | 2003–2004 | 8 | 103 | 61 | 42 | Paraffin-embedded tissue | ✓ | ✓ | 60 months |
Yao et al. (2009) | China | ROS | NI | 8 | 147 | 93 | 54 | Frozen tissue | ✓ | ✗ | – |
China | ROS | 2005 | 8 | 209 | 116 | 93 | Paraffin-embedded tissue | ✓ | ✓ | 66 months | |
Li et al. (2005) | China | ROS | 2004 | 7 | 50 | 22 | 28 | Paraffin-embedded tissue | ✓ | ✗ | – |
Zhao et al. (2009) | China | ROS | 2002–2004 | 6 | 63 | 40 | 23 | Paraffin-embedded tissue | ✓ | ✗ | – |
Zu and Huang (2005) | China | ROS | 2002–2003 | 6 | 60 | 43 | 17 | Paraffin-embedded tissue | ✓ | ✗ | – |
Authors (year) | Stages | Histology | Detecting method | Cut-off value | Positive site | Estimates | Extractions | Statistical analysis | ||
|---|---|---|---|---|---|---|---|---|---|---|
SCC | AC | Others | ||||||||
Huang et al. (2005) | I–IV | 35 | 25 | – | IHC | 10 % staining | Cytoplasm | OR | DDE | Univariate |
Liu et al. (2016) | I–IV | – | 22 | – | IHC | 10 % staining | NI | OR, HR | DDE | Univariate |
Malusecka et al. (2008) | I–III | Not mentioned | IHC | 10 % staining | Cytoplasm | HR | Reported | Multivariate | ||
Tsai et al. (2014) | I–IV | 47 | 17 | – | RT–PCR | Ratio = 1* | NI | HR | Reported | Multivariate |
Wang et al. (2011) | I–III | – | 103 | – | IHC | 5 % staining | Nucleus | OR, HR | DDE | Univariate |
Yao et al. (2009) | I–IV | 147 | – | – | IHC | 25 % staining | NI | OR | DDE | Univariate |
I–IV | 86 | 110 | 13 | IHC | 40 % staining | Cytoplasm | OR, HR | DDE | Univariate | |
Li et al. (2005) | I–IV | 19 | 25 | 6 | IHC | 5 % staining | Cytoplasm | OR | DDE | Univariate |
Zhao et al. (2009) | NI | Not mentioned | IHC | 5 % staining | Cytoplasm | OR | DDE | Univariate | ||
Zu and Huang (2005) | NI | 35 | 25 | – | IHC | 10 % staining | Cytoplasm | OR | DDE | Univariate |