| |
RA patients (N = 8658)
|
OA patients (N = 32,202)
|
RA versus OA
|
|---|
|
Events
|
PYs at risk
|
Events
|
PYs at risk
|
Crude IRR (95 % CI)
|
Adjusted IRRa (95 % CI)
|
|---|
|
CVD (total)
|
673
|
10,946
|
1633
|
43,304
|
1.63 (1.49–1.78)
|
2.12 (1.93–2.32)
|
|
Ischemic heart disease
|
260
|
11,280
|
586
|
44,091
|
1.73 (1.50–2.01)
|
2.16 (1.86–2.50)
|
|
Myocardial infarction
|
53
|
11,481
|
71
|
44,574
|
2.90 (2.03–4.14)
|
3.62 (2.52–5.18)
|
|
Angina pectoris
|
224
|
11,319
|
528
|
44,138
|
1.65 (1.41–1.93)
|
2.05 (1.75–2.40)
|
|
Heart failure
|
358
|
11,234
|
808
|
44,003
|
1.74 (1.53–1.97)
|
2.34 (2.07–2.65)
|
|
Stroke
|
177
|
11,396
|
513
|
44,286
|
1.34 (1.13–1.59)
|
1.68 (1.41–2.00)
|
|
Cerebral infarction
|
136
|
11,433
|
431
|
44,327
|
1.22 (1.01–1.48)
|
1.56 (1.29–1.90)
|
|
Intracerebral hemorrhage
|
32
|
11,506
|
77
|
44,599
|
1.61 (1.07–2.43)
|
1.85 (1.22–2.81)
|
|
Subarachnoid hemorrhage
|
15
|
11,517
|
15
|
44,626
|
3.87 (1.89–7.93)
|
4.45 (2.13–9.26)
|
-
RA rheumatoid arthritis, OA osteoarthritis, PYs patient-years, IRR incidence rate ratio, CI confidence interval, CVD cardiovascular disease
-
aAdjusted by age and sex
