From: Fampridine and quality of life in individuals with multiple sclerosis
Spatiotemporal gait parameters | Non-respondent (n = 35) | Respondent (n = 15) | ||||
---|---|---|---|---|---|---|
Pre 1 | Pre 2 | Post 1 | Pre 1 | Pre 2 | Post 1 | |
Velocity (m s−1) | 1.21 (0.44) | 1.2 (0.48) | 1.27 (0.46) | 0.66 (0.36) | 0.78 (0.48)* | 1.03 (0.51) £ |
Cadence (steps min−1) | 115.11 (23.03) | 113.29 (25.98) | 116.35 (23.83) | 82.03 (27.97) | 90.89 (30.4)** | 104.48 (26.18) £ |
Step length (m) | 0.62 (0.15) | 0.62 (0.16) | 0.64 (0.16) † | 0.46 (0.15) | 0.49 (0.18)** | 0.57 (0.16) £ |
Step time (s) | 0.55 (0.14) | 0.57 (0.17) | 0.54 (0.14) | 0.83 (0.32) | 0.75 (0.28) | 0.62 (0.18)*** |
Step width (m) | 0.13 (0.05) | 0.13 (0.04) | 0.12 (0.04) | 0.14 (0.07) | 0.14 (0.07) | 0.12 (0.06) |
Stance time (% GC) | 64.32 (4.17) | 64.58 (4.83) | 63.55 (4.6) † | 70.01 (5.94) | 68.76 (6.34) | 65.46 (4.12)*** |
Double supp. time (% GC) | 29.1 (8.22) | 29.4 (9.66) | 28.12 (8.12) † | 40.53 (12.23) | 37.76 (12.86) | 31.25 (8.34)*** |