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Table 2 Mean and (SD) of the different indices of the PERSEPP HRQoL questionnaire for all patients before (Pre 1 and Pre 2) and after (Post 1 and Post 2) fampridine

From: Fampridine and quality of life in individuals with multiple sclerosis

PERSEPP (%) (items) All patients (n = 50)
Pre 1 Pre 2 Post 1 Post 2
Overall (33) 62.4 (16.4) 62.5 (16.9) 66.3 (17.6) 68.9 (18.4)*
Social support (5) 87.2 (14.2) 86.5 (16.4) 87.5 (16.7) 88.2 (17)
Relationship dif. (9) 52.2 (22.8) 54.7 (24.1) 59 (24.5) 61.9 (23.2)**
Fatigue (4) 43.5 (30.9) 44 (29.2) 52.4 (32.8)*** 52.8 (34.7)***
State of mind and sleep disorder (7) 63.2 (24.8) 64.3 (26.9) 67.5 (26.6) 69.5 (27.2)
Time perspective (8) 59.2 (22) 57.5 (21.8) 62.4 (24.5) 66.6 (23.5) +
Relapse (15) (n = 29) 48.4 (24.4) 50.6 (23) 53.4 (24) 55.7 (28.2)
Modules     
Coping (8) 58.7 (19.1) 58.1 (19.) 59.6 (21) 59.5 (20.6)
Symptoms (20) 54.6 (17.9) 55.1 (18.6) 59.5 (17.7) 63 (18.8)
Treatment (5) (n = 26) 86.5 (15.7) 78.6 (25) 80.9 (18.1) 88 (13.8) ¥
  1. The italic values correspond statistical significant differences
  2. p 10−4 Pre 1 and Pre 2 versus Post 2
  3. ** p < 0.01 Pre 1 versus Post 2
  4. *** p < 0.05 Pre 1 and Pre 2 versus Post1 and Post 2
  5. + p < 0.01 Pre 1 and Pre 2 versus Post 2
  6. p < 0.05 Pre 1 and Pre 2 versus Post 1, and p: 10−4 Pre 1 and Pre 2 versus Post 2
  7. ¥ p: < 10−3 Post 1 and Post 2