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Table 2 Mean and (SD) of the different indices of the PERSEPP HRQoL questionnaire for all patients before (Pre 1 and Pre 2) and after (Post 1 and Post 2) fampridine

From: Fampridine and quality of life in individuals with multiple sclerosis

PERSEPP (%) (items)

All patients (n = 50)

Pre 1

Pre 2

Post 1

Post 2

Overall (33)

62.4 (16.4)

62.5 (16.9)

66.3 (17.6)

68.9 (18.4)*

Social support (5)

87.2 (14.2)

86.5 (16.4)

87.5 (16.7)

88.2 (17)

Relationship dif. (9)

52.2 (22.8)

54.7 (24.1)

59 (24.5)

61.9 (23.2)**

Fatigue (4)

43.5 (30.9)

44 (29.2)

52.4 (32.8)***

52.8 (34.7)***

State of mind and sleep disorder (7)

63.2 (24.8)

64.3 (26.9)

67.5 (26.6)

69.5 (27.2)

Time perspective (8)

59.2 (22)

57.5 (21.8)

62.4 (24.5)

66.6 (23.5) +

Relapse (15) (n = 29)

48.4 (24.4)

50.6 (23)

53.4 (24)

55.7 (28.2)

Modules

    

Coping (8)

58.7 (19.1)

58.1 (19.)

59.6 (21)

59.5 (20.6)

Symptoms (20)

54.6 (17.9)

55.1 (18.6)

59.5 (17.7)

63 (18.8)

Treatment (5) (n = 26)

86.5 (15.7)

78.6 (25)

80.9 (18.1)

88 (13.8) ¥

  1. The italic values correspond statistical significant differences
  2. p 10−4 Pre 1 and Pre 2 versus Post 2
  3. ** p < 0.01 Pre 1 versus Post 2
  4. *** p < 0.05 Pre 1 and Pre 2 versus Post1 and Post 2
  5. + p < 0.01 Pre 1 and Pre 2 versus Post 2
  6. p < 0.05 Pre 1 and Pre 2 versus Post 1, and p: 10−4 Pre 1 and Pre 2 versus Post 2
  7. ¥ p: < 10−3 Post 1 and Post 2