|
Healthy volunteers
|
PAH patients
|
p value
|
---|
Number, n
|
6
|
9
| |
Age, years
|
45.8 ± 8.9
|
41.8 ± 14.7
|
0.558
|
Gender, n (male/female)
|
4/2
|
1/8
|
0.089
|
Height, cm
|
163.2 ± 10.7
|
157.7 ± 5.8
|
0.288
|
Body weight, kg
|
60.4 ± 11.1
|
53.2 ± 6.4
|
0.234
|
Body mass index, kg/m2
|
22.0 ± 2.5
|
21.4 ± 2.0
|
0.635
|
Body surface area, m2
|
1.63 ± 0.20
|
1.52 ± 0.11
|
0.209
|
IPAH/APAH, n
|
N/A
|
5/4
| |
PDE-5 inhibitors, n (%)
|
N/A
|
8 (88.9)
| |
Endothelin receptor antagonists, n (%)
|
N/A
|
8 (88.9)
| |
Prostanoids, n (%)
|
N/A
|
5 (55.6)
| |
- Data are expressed as n (%) or mean ± standard deviation
-
PAH pulmonary arterial hypertension, IPAH idiopathic pulmonary arterial hypertension, APAH associated pulmonary arterial hypertension, PDE-5 inhibitors phosphodiesterase 5 inhibitors, N/A not available