From: Association between tooth loss and risk of oesophageal cancer: a dose–response meta-analysis
Studies, N | OR (95 % CI) | P value | P of heterogeneity | I 2 (%) | |
---|---|---|---|---|---|
Total | 9 | 1.53 (1.02–2.29) | 0.040 | 0.000 | 72.8 |
Country | |||||
Asia | 4 | 1.38 (0.92–2.07) | 0.118 | 0.112 | 49.9 |
Europe | 2 | 0.84 (0.47–1.52) | 0.570 | 0.536 | 0.0 |
America | 1 | 1.34 (0.78-2.30) | 0.289 | NA | NA |
Latin America | 1 | 1.80 (0.80–4.06) | 0.157 | NA | NA |
Africa | 1 | 5.28 (2.97–9.38) | 0.000 | NA | NA |
Effect size | |||||
OR | 6 | 1.93 (1.14–3.25) | 0.014 | 0.001 | 74.8 |
HR | 2 | 1.05 (0.58-1.88) | 0.880 | 0.196 | 40.3 |
RR | 1 | 0.90 (0.48–1.68) | 0.740 | NA | NA |
Sample size | |||||
Large | 5 | 1.84 (0.99–3.42) | 0.055 | 0.000 | 83.0 |
Small | 4 | 1.19 (0.84–1.71) | 0.329 | 0.410 | 0.0 |
Adjustment for smoking and alcohol drinking | |||||
Yes | 7 | 1.36 (1.06–1.74) | 0.014 | 0.350 | 10.4 |
No | 2 | 1.99 (0.29–13.85) | 0.486 | 0.000 | 94.1 |
NOS score | |||||
High | 8 | 1.29 (1.00–1.67) | 0.053 | 0.244 | 23.3 |
Low | 1 | 5.28 (2.97–9.38) | 0.000 | NA | NA |
Assessment of tooth loss | |||||
Inspected by dentists or interviewers | 5 | 1.25 (0.95–1.64) | 0.113 | 0.413 | 0.0 |
Questionnaires | 3 | 2.13 (0.69–6.58) | 0.190 | 0.000 | 88.3 |
Self-reported | 1 | 1.34 (0.78–2.30) | 0.289 | NA | NA |
Study design | |||||
Case control study | 6 | 1.93 (1.14–3.25) | 0.014 | 0.001 | 74.8 |
Cohort | 3 | 1.02 (0.71–1.46) | 0.910 | 0.385 | 0.0 |