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Table 1 Characteristic of studies included in the meta-analysis

From: Association between tooth loss and risk of oesophageal cancer: a dose–response meta-analysis

Study

Year

Country

Study design

No. of subjects

No. of patients

Sex

Age, median (range), years

Assessment of tooth loss

Adjustment for covariates

Abnet

2001

China

A prospective cohort study

28,868

620

W and M

NA (40–69)

Questionnaire and clinical examination by interviewer

Adjusted for age sex, tobacco use, and alcohol use

Abnet

2005

Finland

A prospective cohort study

29,124

49

M

57.2 (50–69)

Questionnaire

Adjusted for age at randomization and education

Guha

2007

Central Europe

A hospital-based case–control study

1060

132

W and M

NA (NA)

Inspected by dentist or interviewer

Adjusted for age, sex, country/center, education, tobacco pack-years, cumulative alcohol consumption, and all other oral health variables

Guha

2007

Latin American

A hospital-based case–control study

1978

173

W and M

NA (NA)

Inspected by dentist or interviewer

Adjusted for age, sex, country/center, education, tobacco pack-years, cumulative alcohol consumption, and all other oral health variables

Abnet

2008

Iran

A population-based case–control study

843

283

W and M

65 (56–73)

Inspected by trained medical personnel

Adjusted for age, sex, place of residence, ethnicity, alcohol drinking, use of tobacco, opium, or both, education in three categories, number of appliances, and fruit and vegetable intake

Hiraki

2008

Japan

A hospital-based case–control study

1062

354

W and M

58.0 (20–79)

Self-administered questionnaire

Adjusted for age, sex, smoking and drinking status (never, former, current), vegetable and fruit intake, BMI, and regular exercise

Michaud

2008

United states

A prospective cohort study

48,375

131

M

NA (40–75)

Self-reported and clinical examination

Adjusted for age (continuous), race (White, Asian, Black), physical activity (quintiles), history of diabetes (yes/no), alcohol (quartiles), body mass index (<22, 22–24,9, 25–29.9, 30+), geographic location (South, West, Northeast, Midwest), height (quintiles), calcium intake (quintiles), total caloric intake (quintiles), red meat intake (quintiles),fruit and vegetable intake (quintiles), and vitamin D score (deciles) smoking history (never, past quit ≤10 years, past quit >10 years, current 1–14 cigarettes per day, 15–24 cigarettes per day, 25+ cigarettes per day), and pack-years (continuous)

Dar

2013

India

A case–control study

2367

703

W and M

Case: 61.6; Control: 59.8

Inspected by dentist

Adjusted for age, ethnicity, residence, education, wealth score, fruit and vegetable intake, bidi smoking, gutka chewing, alcohol consumption andcumulative use of hookah, cigarette, and nass

Patel

2013

Kenya

A hospital-based case–control study

318

159

W and M

56.1 (NA)

Questionnaire

Unadjust

  1. NA not available, M male, W female