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Table 2 Correlation among the MMSE score, the z-score of the parahippocampal gyrus, diffusion tensor parameters (FA, ADC) of the uncinate fascicles on both sides compared with those of the next periods

From: Diffusion tensor studies and voxel-based morphometry of the temporal lobe to determine the cognitive prognosis in cases of Alzheimer’s disease and mild cognitive impairment: Do white matter changes precede gray matter changes?

  MMSE z-score R-FA R-ADC L-FA L-ADC Next MMSE Next z-score Next R-FA Next R-ADC Next L-FA Next L-ADC
MMSE   −0.42 0.40 −0.38 0.49 −0.45 0.87 −0.47 0.29 −0.40 0.28 −0.39
z-score P < 0.01   −0.04 0.35 0.09 0.34 −0.49 0.88 −0.08 0.27 −0.03 0.16
R-FA P < 0.01 NS   −0.49 0.67 −0.36 0.46 −0.05 0.56 −0.35 0.48 −0.33
R-ADC P < 0.01 P < 0.05 P < 0.001   −0.25 0.74 −0.37 0.46 −0.33 0.76 −0.31 0.70
L-FA P < 0.001 NS P < 0.001 NS   −0.35 0.51 0.07 0.52 −0.28 0.55 −0.25
L-ADC P < 0.01 P < 0.05 P < 0.05 P < 0.001 P < 0.05   −0.50 0.39 −0.47 0.78 −0.31 0.81
Next MMSE P < 0.001 P < 0.001 P < 0.01 P < 0.05 P < 0.001 P < 0.001   −0.52 0.32 −0.38 0.32 −0.42
Next z-score P < 0.001 P < 0.001 NS P < 0.01 NS P < 0.01 P < 0.001   −0.05 0.37 −0.02 0.27
Next R-FA NS NS P < 0.001 P < 0.05 P < 0.001 P < 0.01 P < 0.05 NS   −0.51 0.67 −0.46
Next R-ADC P < 0.01 NS P < 0.05 P < 0.001 NS P < 0.001 P < 0.01 P < 0.05 P < 0.001   −0.31 0.78
Next L-FA NS NS P < 0.001 P < 0.05 P < 0.001 P < 0.05 P < 0.05 NS P < 0.001 P < 0.05   −0.39
Next L-ADC P < 0.01 NS P < 0.05 P < 0.001 NS P < 0.001 P < 0.01 NS P < 0.01 P < 0.001 P < 0.01