Decoding options and accuracy of translation of developmentally regulated UUA codon in Streptomyces: bioinformatic analysis

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Table 3 Translation and mistranslation rates for six leucine codons in Streptomyces

Codon	Cognates	Pseudo-cognates	Near-cognates	S. coelicolor		S. albus		S. ghananensis		S. clavuligerus		S. venezuelae		S. lividans
Codon	Cognates	Pseudo-cognates	Near-cognates	Rc	Rn	Rc	Rn	Rc	Rn	Rc	Rn	Rc	Rn	Rc	Rn
CUA	UAG	AAG	CAG, GAG, UUG, UCG, UGG, UAA, UAU, UAC	2.067	0.007	2.067	0.009	2.067	0.009	2.067	0.009	2.067	0.010	2.067	0.007
CUC	GAG	AAG	UAG, CAG, GUG, GCG, GGG, GAA, GAU, GAC	4.134	0.014	4.134	0.014	4.134	0.012	4.134	0.014	6.201	0.012	4.134	0.011
CUG	CAG	UAC	AAG, UAG, GAG, CUG, CCG, CGG, CAA, CAU, CAC	2.068	0.019	2.068	0.020	2.068	0.019	2.068	0.019	2.068	0.019	2.068	0.019
CUU	AAG	GAG, UAG	CAG, AUG, ACG, AGG, AAA, AAU, AAC	–	–	–	–	–	–	–	–	–	–	–	–
UUA	UAA	AAA	CAA, GAA, UUA, UCA, UGA, UAU, UAC, UAG	2.067	0.006	2.067	0.006	2.067	0.006	2.067	0.006	2.067	0.006	2.067	0.006
UUG	CAA	UAA	AAA, GAA, CUA, CCA, CGA, CAU, CAC, CAG	2.068	0.014	2.068	0.015	2.068	0.014	2.068	0.014	2.068	0.013	2.068	0.014