Table 4 Estimated mean change in HRQOL, fatigue and physical activity from baseline to follow-up among patients with unimproved versus improved work status
Changes within the improved group (N = 68) | Changes within the unimproved group (N = 38) | |||
|---|---|---|---|---|
Mean change | p value | Mean change | p value | |
EORTC QLQ-C30 functions (mean SD) | ||||
Physical functioning (PF) | 8.5 | <0.001 | 6.1 | 0.022 |
Role functioning (RF) | 25.8 | <0.001 | 17.6 | <0.001 |
Emotional functioning (EF) | 9.0 | <0.001 | 5.4 | 0.06 |
Cognitive functioning (CF) | 5.4 | 0.017 | 3.9 | 0.36 |
Social functioning (SF) | 18.4 | <0.001 | 8.8 | 0.09 |
Global health and quality of life (GQL) | 14.1 | <0.001 | 7.2 | 0.035 |
EORTC QLQ-C30 symptoms (mean SD) | ||||
Fatigue | −17.9 | <0.001 | −18.3 | 0.001 |
Nausea/vomiting | −2.7 | 0.040 | −2.3 | 0.34 |
Pain | −9.7 | 0.003 | 1.3 | 0.79 |
Dyspnea | −14.9 | <0.001 | −7.2 | 0.15 |
Sleep problems | −11.6 | 0.002 | − 0.9 | 0.87 |
Appetite loss | −9.0 | 0.002 | −5.4 | 0.25 |
Constipation | −5.6 | 0.15 | 1.9 | 0.69 |
Diarrhea | −4.0 | 0.15 | −1.9 | 0.76 |
Financial problems | 1.5 | 0.58 | 10.8 | 0.012 |
Fatigue Questionnaire (mean SD) | ||||
Physical fatigue (P-Fat) | −3.1 | <0.001 | −3.3 | <0.001 |
Mental fatigue (M-Fat) | −0.4 | 0.08 | −0.2 | 0.48 |
Total fatigue (T-Fat) | −3.5 | <0.001 | −3.5 | <0.001 |
Physical activity index | 0.2 | 0.33 | 0.7 | 0.022 |