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Table 1 Bacterial strains and features

From: Antibacterial activities and structure–activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes

Bacterial strain

Relevant features

Reference

Escherichia coli

ATCC 8739 and ATCC 10536

Reference strains

 

 AG100

Wild-type E. coli K-12

Viveiros et al. (2005)

 AG100ATet

ΔacrAB mutant of AG100; TETR owing to acrF gene markedly overexpressed

Elkins and Mullis (2007)

 AG102

AG100 over-expressing AcrAB pump

 

Enterobacter aerogenes

ATCC 13048

Reference strain

 

EA-CM64

CHLR variant obtained from

Ghisalberti et al. (2005)

EA3

ATCC 13048 overexpressing AcrAB pump

Pradel and Pagès (2002)

 

Clinical MDR isolate exhibiting energy-dependent

 
 

Norfloxacin and chloramphenicol efflux with KANR AMPR

 
 

NALR STRR TETR

 

EA27

Clinical MDR isolate exhibiting

 
 

Energy-dependent NOR and

 
 

CHL efflux; KANR AMPR NALR

 
 

STRR TETR

 

EA289

KAN-sensitive derivative of EA27

 

EA294

EA289 acrA::KANR

 

EA289

EA289 tolC::KANR

 

Klebsiella pneumoniae

ATCC 11296

Reference strain

 

Kp55

Clinical MDR isolate, TETR

Chevalier et al. (2000)

Kp63

AMPR ATMR CEFR

 
 

Clinical MDR isolate, TETR CHLR

 
 

AMPR ATMR

 

Pseudomonas aeruginosa

  

PA01

Reference strain

 

PA124

MDR clinical isolate

Lorenzi et al. (2009)

Staphyloccocus aureus

  

ATCC1026

Reference strain

 

SA3

Clinical Laboratory isolate, sensitive to methicilin

 

SA4

  

SA11

  

SA12

Clinical laboratory isolate, METR

 

MRSA 3

 

Dzoyem et al. (2013)

MRSA 4

  

MRSA 6

  

MRSA 8

  
  1. KAN kanamycin, TET tetracycline, CHL chloramphenicol, NOR norfloxacin, AMP ampicillin, MET methicillin, NAL nalidixic acid, STR streptomycin, ATM aztreonam, CEF cefalothin, R resistant, MDR multidrug-resistant