Fig. 1

GDA results (Cases 6 and 11). The x-axis indicates array spots of BAC clones ordered from chromosomes 1–22, X and Y. The y-axis shows the fluorescence ratio of differently labeled sample/control DNA. The color bars indicate the regions of genetic diseases included in the respective GDA. a In Case 6, copy-number gain was recognized on all clones of chromosome 16 and X/Y signal patterns indicated that the case has the reverse gender to control. Accordingly, this case was estimated as a female with trisomy 16. b Case 11 was estimated as trisomy 15 with unsatisfactory signals on X/Y regions as indicated by a dotted line box. Each arrow indicates duplication signals on the corresponding chromosomal region