Table 1 Clinical factors and its associations with insomnia in recurrent glioma patients
From: Insomnia and its associations in patients with recurrent glial neoplasms
Characteristic | Insomnia Absent (N = 181) | Insomnia Present (N = 159) | Total (N = 340) | p-value* |
|---|---|---|---|---|
Age | 0.6601 | |||
N | 181 | 159 | 340 | |
Median | 50.0 | 50.0 | 50.0 | |
Gender | 0.9087 | |||
Male | 119 (65.7 %) | 106 (66.7 %) | 225 (66.2 %) | |
Female | 62 (34.3 %) | 53 (33.3 %) | 115 (33.8 %) | |
Race | 0.8122 | |||
Caucasian | 172 (95.0 %) | 150 (94.3 %) | 322 (94.7 %) | |
Other race | 9 (5.0 %) | 9 (5.7 %) | 18 (5.3 %) | |
Histology | 0.1483 | |||
High-grade glioma | 153 (84.5 %) | 143 (89.9 %) | 296 (87.1 %) | |
Low-grade glioma | 28 (15.5 %) | 16 (10.1 %) | 44 (12.9 %) | |
Side of brain affected | 0.1585 | |||
Right | 83 (45.9 %) | 80 (50.3 %) | 163 (47.9 %) | |
Left | 82 (45.3 %) | 73 (45.9 %) | 155 (45.6 %) | |
Bilateral | 16 (8.8 %) | 6 (3.8 %) | 22 (6.5 %) | |
KPS | 0.0793 | |||
50–80 | 79 (44.6 %) | 86 (54.8 %) | 165 (49.4 %) | |
90–100 | 98 (55.4 %) | 71 (45.2 %) | 169 (50.6 %) | |
Number of progressions | 0.4868 | |||
1 | 91 (50.3 %) | 87 (54.7 %) | 178 (52.4 %) | |
2 | 51 (28.2 %) | 46 (28.9 %) | 97 (28.5 %) | |
3+ | 39 (21.5 %) | 26 (16.4 %) | 65 (19.1 %) | |
Corticosteroid use | 0.0003 | |||
Yes | 59 (32.6 %) | 83 (52.2 %) | 142 (41.8 %) | |
No | 122 (67.4 %) | 76 (47.8 %) | 198 (58.2 %) | |
Antidepressant use | >0.999 | |||
Yes | 53 (29.3 %) | 46 (28.9 %) | 99 (29.1 %) | |
No | 128 (70.7 %) | 113 (71.1 %) | 241 (70.9 %) | |
Stimulant use | >0.999 | |||
Yes | 15 (8.3 %) | 14 (8.8 %) | 29 (8.5 %) | |
No | 166 (91.7 %) | 145 (91.2 %) | 311 (91.5 %) | |
Sleep aid use | 0.0764 | |||
Yes | 29 (16.0 %) | 38 (23.9 %) | 67 (19.7 %) | |
No | 152 (84.0 %) | 121 (76.1 %) | 273 (80.3 %) | |
Antipsychotic use | >0.999 | |||
Yes | 3 (1.7 %) | 2 (1.3 %) | 5 (1.5 %) | |
No | 178 (98.3 %) | 157 (98.7 %) | 335 (98.5 %) | |
Anti-epileptic use | 0.0725 | |||
Yes | 131 (72.4 %) | 129 (81.1 %) | 260 (76.5 %) | |
No | 50 (27.6 %) | 30 (18.9 %) | 80 (23.5 %) | |
Symptom: fatigue | 0.0501 | |||
Absent | 33 (18.2 %) | 17 (10.7 %) | 50 (14.7 %) | |
Present | 148 (81.8 %) | 142 (89.3 %) | 290 (85.3 %) | |
Symptom: sedation | 0.8895 | |||
Absent | 131 (72.4 %) | 114 (71.7 %) | 245 (72.1 %) | |
Present | 50 (27.6 %) | 45 (28.3 %) | 95 (27.9 %) | |
Symptom: confusion | 0.5697 | |||
Absent | 127 (70.2 %) | 116 (73.0 %) | 243 (71.5 %) | |
Present | 54 (29.8 %) | 43 (27.0 %) | 97 (28.5 %) | |
Symptom: mood disturbance | 0.2438 | |||
Absent | 107 (59.1 %) | 84 (52.8 %) | 191 (56.2 %) | |
Present | 74 (40.9 %) | 75 (47.2 %) | 149 (43.8 %) |