Table 5 Subgroup analysis of patients with mitral valve operation
From: Association of inflammatory gene polymorphisms with mechanical heart valve reoperation
Gene polymorphisms (minor allele frequency) | Patient number | p value | OR (95 % CI) | |
|---|---|---|---|---|
Number of heart valve operations | ||||
1 | ≥2 | |||
IL1B rs16944 (0.45) | ||||
AA, AG | 65 | 15 | 0.510 | 1 |
GG | 25 | 8 | 1.387 (0.523–3.673) | |
IL6 rs1800796 (0.26) | ||||
GG | 22 | 1 | 0.692 | 1 |
GC, CC | 83 | 7 | 1.855 (0.217–15.886) | |
IL10 rs1800871 (0.27) | ||||
AA, AG | 79 | 22 | 0.466 | 1 |
GG | 9 | 1 | 0.399 (0.048–3.332) | |
IL10 rs1800896 (0.06)a | ||||
TT, TC | 88 | 23 | 0.205 | |
CC | 0 | 1 | ||
IFNG rs2430561 (0.08) | ||||
AA | 76 | 20 | 1.000 | 1 |
AT, TT | 13 | 3 | 0.877 (0.228–3.378) | |
TNFA rs1800629 (0.04) | ||||
GG | 80 | 23 | 0.471 | 1 |
GA, AA | 9 | 1 | 0.409 (0.049–3.405) | |
TGFB1 rs1800470 (0.46) | ||||
GG, GA | 20 | 10 | 0.043 | 1 |
AA | 69 | 13 | 0.377 (0.144–0.987) | |
CRP rs1205 (0.40) | ||||
CC, CT | 61 | 10 | 0.031 | 1 |
TT | 29 | 13 | 2.734 (1.073–6.969) | |