Table 1 SNP information
From: Association of inflammatory gene polymorphisms with mechanical heart valve reoperation
Gene rs number | Global minor allele frequency | Functional consequence | Direction | Primer sequence |
|---|---|---|---|---|
IL1B rs16944 | G = 0.4906 | Upstream variant 2 KB | Fa | CCAGCCAAGAAAGGTCAAT |
Rb | GAAGAGGTTTGGTATCTGCCA | |||
Gc | CAATTGACAGAGAGCTCC | |||
IL10 rs1800871 | A = 0.4347 | Upstream variant 2 KB | F | GAAACCAAATTCTCAGTTGGC |
R | ATGACCCCTACCGTCTCTATTT | |||
G | TGGTGTACCCTTGTACAGGTGATGTAA | |||
IL10 rs1800896 | C = 0.2722 | Intron variant | F | ACACACACACAAATCCAAG |
R | ATAGGAGGTCCCTTACTTTCCTC | |||
G | TCCTCTTACCTATCCCTACTTCCCC | |||
IFNG rs2430561 | A = 0.2802 | Intron variant | F | ATATTCAGACATTCACAATTGATT |
R | TATTATACGAGCTTTAAAAGATAGTTCC | |||
G | TTTATXCTTACAACACAAAATCAAATC | |||
TNFA rs1800629 | A = 0.0903 | Upstream variant 2 KB | F | AGAAGGAAACAGACCACAGAC |
R | GGGAAAGAATCATTCAACCA | |||
G | TAGGTTTTGAGGGGCATG | |||
TGFB1 rs1800470 | G = 0.4547 | Missense | F | GCCCATCTAGGTTATTTCC |
R | TGCCAGTCACTTCCTACC | |||
G | AGCAGCGGTAGCAGCAGC | |||
CRP rs1205 | T = 0.3383 | UTR variant 3 prime | F | ATCTTYTTGCTGCTGGATTTC |
R | TTGTTTGTCAATCCCTTGG | |||
G | CTTGTTTGCCACATGGWGAGAGACT |