Pooled bioequivalence study database from Turkey: characterization of adverse events and determination of split points based on Gini Index as a promising method

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Table 6 Results observed above/below split points for AUC values in terms of ATC subgroups

AUC	Number of adverse events		Number of subjects		Probabilities
ATC subgroups	Below split point	Above split point	Below split point	Above split point	Below split point	Above split point
Cardiovascular system	15	19	216	111	0.069	0.171
Antiinfectives for systemic use	10	15	164	247	0.061	0.061
Musculo-skeletal system	7	14	81	243	0.086	0.058
Alimentary tract and metabolism	19	74	126	224	0.151	0.330
Nervous system	50	87	218	219	0.229	0.397
Respiratory system	10	1	41	55	0.244	0.018
Genito-urinary system and sex hormones	5	25	15	32	0.333	0.781

Probabilities are calculated by number of adverse events below (above) the split point/number of subjects below (above) the split point, and higher probabilities given in italic font