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Table 6 Results observed above/below split points for AUC values in terms of ATC subgroups

From: Pooled bioequivalence study database from Turkey: characterization of adverse events and determination of split points based on Gini Index as a promising method

AUC Number of adverse events Number of subjects Probabilities
ATC subgroups Below split point Above split point Below split point Above split point Below split point Above split point
Cardiovascular system 15 19 216 111 0.069 0.171
Antiinfectives for systemic use 10 15 164 247 0.061 0.061
Musculo-skeletal system 7 14 81 243 0.086 0.058
Alimentary tract and metabolism 19 74 126 224 0.151 0.330
Nervous system 50 87 218 219 0.229 0.397
Respiratory system 10 1 41 55 0.244 0.018
Genito-urinary system and sex hormones 5 25 15 32 0.333 0.781
  1. Probabilities are calculated by number of adverse events below (above) the split point/number of subjects below (above) the split point, and higher probabilities given in italic font