Skip to main content

Table 2 Frequency of adverse events according to the drug subgroups

From: Pooled bioequivalence study database from Turkey: characterization of adverse events and determination of split points based on Gini Index as a promising method

Drug subgroup (ATC classes) Number of studies Number of volunteers Number of adverse events Adverse event frequency per volunteer (%)
Cardiovascular system 66 2095 355 16.9
Antiinfectives for systemic use 56 1409 126 8.9
Musculo-skeletal system 46 1595 108 6.8
Alimentary tract and metabolism 42 1280 276 21.6
Nervous system 39 1121 681 60.8
Respiratory system 8 228 27 11.8
Genito-urinary system and sex hormones 2 48 48 100
Antineoplastic and immunomodulating agents 2 52 21 40.4
Total 261 7828 1642 21
  1. ATC anatomical therapeutical classification (Investigation 1994)