Pooled bioequivalence study database from Turkey: characterization of adverse events and determination of split points based on Gini Index as a promising method

SpringerPlus

Table 2 Frequency of adverse events according to the drug subgroups

Drug subgroup (ATC classes)	Number of studies	Number of volunteers	Number of adverse events	Adverse event frequency per volunteer (%)
Cardiovascular system	66	2095	355	16.9
Antiinfectives for systemic use	56	1409	126	8.9
Musculo-skeletal system	46	1595	108	6.8
Alimentary tract and metabolism	42	1280	276	21.6
Nervous system	39	1121	681	60.8
Respiratory system	8	228	27	11.8
Genito-urinary system and sex hormones	2	48	48	100
Antineoplastic and immunomodulating agents	2	52	21	40.4
Total	261	7828	1642	21