Table 1 Clinicopathologic characteristics and PD-L1 protein expression status
Characterics | PD-L1 expression (n = 25) | PD-L1 no expression (n = 158) | P value |
|---|---|---|---|
Age (years, median) | 0.06 | ||
<50 | 16 (64.0 %) | 70 (44.3 %) | |
≥50 | 9 (36.0 %) | 88 (55.7 %) | |
Menopausal status | 0.57‡ | ||
Pre-menopausal | 22 (88.0 %) | 132 (83.5 %) | |
Post-menopausal | 3 (12.0 %) | 26 (16.5 %) | |
LNM | 0.83 | ||
Present | 8 (32.0 %) | 54 (34.2 %) | |
Absent | 17 (68.0 %) | 104 (65.8 %) | |
Tumor grade | <0.0001§ | ||
G1 | 0 (0 %) | 3 (1.9 %) | |
G2 | 1 (4.0 %) | 70 (44.3 %) | |
G3 | 24 (96.0 %) | 85 (53.8 %) | |
Tumor type | 0.25§ | ||
Ductal NOS | 21 (84.0 %) | 146 (92.4 %) | |
ILC | 0 (0 %) | 1 (0.6 %) | |
Other | 4 (16.0 %) | 11 (7.0 %) | |
Basal-like subtype | 0.94 | ||
Yes | 16 (64.0 %) | 100 (63.3 %) | |
No | 9 (36.0 %) | 58 (36.7 %) | |
Tumor embolus | 0.32‡ | ||
Yes | 1 (4.0 %) | 21 (13.3 %) | |
No | 24 (96.0 %) | 137 (86.7 %) | |
Tumor size | 0.06† | ||
Mean (SD) | 2.28 ± 0.91 | 2.74 ± 1.13 | |
Median | 2.20 | 2.5 | |
Range | 0.70–4.30 | 0.80–8.0 |