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Table 5 Factors related to grading of necroinflammatory activity (G3–G4 vs. G0–G2): univariate analysis and multivariate analysis

From: Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis

Factors

Univariate analysis

Multivariate analysis

OR

95 % CI

p

OR

95 % CI

p

TB (mg/dl)

 5.2>

1 (Ref)

  

1 (Ref)

  

 5.2<

7.50

0.91–61.93

0.061

4.73

0.12–178.76

0.402

IL-21 (pg/ml)

 296>

1 (Ref)

  

1 (Ref)

  

 296<

31.50

2.53–392.92

<0.01*

23.94

1.15–499.49

<0.05*

CCL20 (pg/ml)

 71>

1 (Ref)

  

1 (Ref)

  

 71<

12.25

1.35–111.01

<0.05*

1.23

0.03–43.26

0.910

  1. Ref reference group, IL-21 interleukin 21, CCL20 C–C chemokine ligand 20
  2. p values were calculated with multiple logistic regression analysis (*statistically significant)