From: Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis
 | Grading of necroinflammatory activity: G0–2 (n = 11) | Grading of necroinflammatory activity: G3–4 (n = 8) | p |
---|---|---|---|
ALT (U/l) | 420 ± 426 | 818 ± 1088 | 0.3484 |
Alb (g/dl) | 3.5 ± 0.8 | 3.0 ± 0.8 | 0.0860 |
TB (mg/dl) | 3.2 ± 6.4 | 11.0 ± 9.6 | <0.05* |
PT (%) | 68.7 ± 28.4 | 74.1 ± 18.6 | 0.9150 |
PLT (×104/μl) | 16.5 ± 6.2 | 13.1 ± 4.2 | 0.2014 |
IgG (mg/dl) | 2307 ± 1131 | 2836 ± 548 | 0.1767 |
IL-21 (pg/ml) | 211.7 ± 135.3 | 414.9 ± 142.7 | <0.01* |
IL-18 (pg/ml) | 903.8 ± 667.4 | 1069.2 ± 891.9 | 0.8910 |
CCL20 (pg/ml) | 55.4 ± 62.5 | 329.3 ± 302.8 | <0.01* |
CCR6 (pg/ml) | 113.3 ± 112.6 | 142.5 ± 99.1 | 0.4381 |
CXCL9 (pg/ml) | 1356.8 ± 1036.9 | 2020.8 ± 963.6 | 0.1084 |
CXCR3 (ng/ml) | 51.7 ± 43.6 | 82.9 ± 41.6 | 0.1084 |