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Table 3 Relationship between serum IL-21 levels and clinical presentation in patients with autoimmune hepatitis

From: Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis

Variable

r

p

AST (U/l)

0.2716

0.2215

ALT (U/l)

0.2433

0.2753

ALP (U/l)

0.2366

0.2890

Alb (g/dl)

−0.4951

<0.05*

TB (mg/dl)

0.4641

<0.05*

PT (%)

−0.3587

0.1103

PLT (×104/μl)

−0.2981

0.1778

IgG (mg/dl)

0.2928

0.1860

ANA (median)

0.0335

0.8853

IL-18 (pg/ml)

0.1158

0.6079

CCL20 (pg/ml)

0.5987

<0.005*

CCR6 (pg/ml)

0.4151

0.0547

CXCL9 (pg/ml)

0.4999

<0.05*

CXCR3 (ng/ml)

0.5016

<0.05*

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, IgG immunoglobulin G, ANA antinuclear antibody, IL-18 interleukin-18, CCL20 C–C chemokine ligand 20, CCR6 C–C chemokine receptor 6, CXCL9 CXC chemokine ligand 9, CXCR3 CXC chemokine receptor 3
  2. p values were calculated with the Spearman rank correlation test (*statistically significant)
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