Fig. 1

Schematic for induction of airway inflammation and treatment with WGP. PBS or 400 μg WGP in PBS was orally administered to mice daily via oral gavage or pipette feeding. Oral administration of PBS or WGP began 7 days prior to sensitization with ovalbumin (OVA)/Alum and continued daily for the duration of the experiment. Mice were sensitized via i.p. injection of 100 μg OVA in 1.8–2.6 mg Alum on Days 0 and 14. Mice were challenged with OVA (1 % w/v in PBS) for 20 min using a nebulizer on Days 24, 25, 26 and 27. Mice were euthanized 24 h following the last challenge