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Table 3 Comparison of intensity (see Methods) of phosphoprotein spots selected from Fig. 2/Table 2 for increased abundance and/or variation (SD) in human versus rodent hearts

From: Global comparison of phosphoproteins in human and rodent hearts: implications for translational studies of myosin light chain and troponin phosphorylations

Spot Protein Overall mean Overall SD Human mean Human SD Rat mean Rat SD t p value
1 Cerulpolasmin 63.42 36.12 52.62 25 90.42 49.19 (−) 1.46 0.224
3 ER ATPs e 78.88 46.56 67.45 47.78 107.47 31.94 (−) 1.82 0.104
13 60kD Heat Shock Protein 84.1 32.7 93.82 32.83 59.78 17.21 2.52 0.0289
15 Haptagloblin 85.05 27.84 85.85 28.69 83.06 29.69 0.16 0.8784
16 Actin, alpha cardiac muscle 1 120.84 48.81 122.79 36.78 115.99 78.87 0.17 0.8777
18 Troponin T cardiac muscle 158.51 53.09 134.45 36.39 218.68 38.55 (−) 3.75 0.0119
23 Tropomyosin alpha-1 chain 202.96 44.58 192.67 46.69 228.7 28.9 (−) 1.74 0.1144
25 Myos in light chain 3 99.82 94.05 43.03 14.26 241.81 9.55 (−) 30.27 <0.0001
27 Peroxiredoxin-2 26.18 14.6 31.63 13.86 12.56 1.29 4.3 0.0018
29 Haptagloblin 22.23 28.72 29.04 31.74 5.21 3.36 2.34 0.0425
  1. Spot number—Fig. 2, protein-identification—Table 2; Overall mean/SD—mean and standard deviation of intensity of spots from composite rectified 2D-DIGE images of phosphoproteins from rodent and human hearts (Fig. 3). t—t value for human versus rodent