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Table 2 Phosphoprotein spots selected for greatest abundance and/or variation (SD) from 2D-DIGE composite and rectified images of human control and failing hearts (Fig. 2) and identified by MALDI-TOF/TOF mass spectrometry (CI > 99 %)

From: Global comparison of phosphoproteins in human and rodent hearts: implications for translational studies of myosin light chain and troponin phosphorylations

Sport number Top ranked protein name (species) Accession no. Protein MW Protein PI Protein Count Protein Score Protein Score CI% Total ion score Total ion CI%
1 Ceruoplasmin OS = Homo sapiens GN = CP PE = 1 SV = 1 CERU-HUMAN 1,22,128 5.4 23 183 100 83 100
3 Transitional endoplascim reticulum ATP ase OS = Homo sapiens GN = VCP PE = 1 SV =  TERA_HUMAN 89,266 5.1 36 413 100 149 100
13 60 kDa heat shock rotein, mitochondrial OS = Homo sapiens GN = HSPD1 PE = 1 SV =  CH60_HUMAN 61,016 5.7 25 831 100 646 100
15 Haptoglobin OS = Homo sapiens GN = HP PE = 1 SV = 1 HPT_HUMAN 45,177 6.1 10 166 100 119 100
16 Actin, alpha cardiac muscle 1 OS = Homo sapiens GN = ACTC1 PE = 1 SV =  ACTC_HUMAN 41,992 5.2 18 701 100 562 100
18 Troponin T, cardiac muscle OS = Homo sapiens GN = TNNT2 PE = 1 SV = 3 TNNT2_HUMAN 35,902 4.9 20 755 100 574 100
23 Tropomyosin alph-1 chain OS = Homo sapiens GN = TPM 1 PE = 1 SV = 2 TPM1_HUMAN 32,689 4.7 23 521 100 339 100
25 Myosin light chain 3 OS = Homo spaiens GN = MYL# PE = 1 SV = 3 MYL3_HUMAN 21,918 5 14 316 100 214 100
27 Peroxiredoxin-2 OS = Homo sapiens GN = PRDX2 PE = 1 SV = 5 PRDX2_HUMAN 21,878 5.7 15 513 100 378 100
29 Haptoglobin OS = Homo sapiens GN = HP PE = 1 SV = 1 HPT_HUMAN 45,177 6.1 6 78 100 53 100
  1. Spot number corresponds to Fig. 2