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Table 2 Serum and CSF CXCL13 concentrations in patients with different type of neurosyphilis

From: CXCL13 chemokine as a promising biomarker to diagnose neurosyphilis in HIV-negative patients

Type of NS

No %

Serum CXCL13 (pg/mL)

CSF CXCL13 (pg/mL)

CXCL13 index

Asymptomatic NS

15 % (6/40)

99.625 ± 51.757

10.458 ± 10.412

18.207 ± 14.652

Syphilitic meningitis

40 % (16/40)

166.034 ± 103.049

12.108 ± 8.129

71.767 ± 234.272

Meningovascular syphilis

15 % (6/40)

118.4201 ± 64.751

37.526 ± 70.852

62.473 ± 99.766

General paresis

25 % (10/40)

170.565 ± 93.286

33.405 ± 47.882

37.426 ± 55.628

Tabes dorsalis

5 % (2/40)

102.769 ± 81.190

17.804 ± 22.632

34.548 ± 42.221

χ2 value

 

5.226

0.334

3.190

P value

 

0.265

0.987

0.527

  1. Kruskal–Wallis H test was used to determine differences among different types of neurosyphilis