Entry | Amount of NH4Cl (mol%) | Yielda (%) |
---|
1 | 5 | 80 |
2 | 10 | 92 |
3 | 15 | 92 |
4 | 20 | 89 |
5 | 25 | 85 |
- The reaction was carried out with ethyl 2′-amino-3′-cyano-1-((diphenylamino)methyl)-6′-methyl-2-oxospiro[indoline-3,4′-pyran]-5′-carboxylate (3a) (10 mmol) and 2-hydroxybenzaldehydes (4a) (10 mmol), and NH4Cl in 10 mL ethanol at refluxing temperature/2 h
-
aIsolated yield of (5a)