Pressure-controlled inverse ratio ventilation as a rescue therapy for severe acute respiratory distress syndrome

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Table 2 Ventilator parameters, hemodynamics, and the dose of noradrenaline before and after IRV

	Pplat^a (cmH₂O)	PEEP (cmH₂O)	Frequency (breaths/min)	Systolic BP (mmHg)	Mean BP (mmHg)	Noradrenaline (µg/kg/min)
Before IRV	26 ± 6	11 ± 5^b	17 ± 7	103 ± 21	76 ± 16	0.135 ± 0.216
1 h after IRV	37 ± 6	20 ± 5	40 ± 9	108 ± 13	83 ± 14	0.130 ± 0.150
6 h after IRV	35 ± 4	18 ± 4	39 ± 9	112 ± 20	81 ± 12	0.110 ± 0.142
12 h after IRV	34 ± 3	17 ± 3	38 ± 10	119 ± 21	84 ± 15	0.102 ± 0.133
24 h after IRV	34 ± 4	17 ± 3	41 ± 13	120 ± 14	85 ± 10	0.076 ± 0.100

Data are presented mean ± SD
Pplat plateau pressure, PEEP positive end-expiratory pressure, BP blood pressure, IRV inverse ratio ventilation
^aPplat is calculated regardless of the modality
^bAveraged PEEP is calculated in the patients ventilated with ACV