Table 1 Epidemiologic and clinical characteristics of 80 patients with P. aeruginosa infection from blood or sterile isolates
Variable | Carbapenem sensitive isolates (N = 59) | Carbapenem resistant isolates (N = 21) | p value |
|---|---|---|---|
Age (years) | |||
Median (range) | 55 (22–88) | 57 (26–77) | 0.86 |
Gender | |||
Male (%) | 66 | 52 | 0.30 |
Race | |||
Caucasian (%) | 81 | 86 | 0.75 |
African American (%) | 12 | 14 | 0.69 |
Ethnicity | |||
Hispanic (%) | 12 | 10 | 1.00 |
Type of acquisition | |||
Hospital acquired (%) | 44 | 71 | 0.04 |
Health care associated (%) | 42 | 24 | 0.19 |
Community acquired (%) | 14 | 5 | 0.43 |
Underlying co-morbidities | |||
Chronic renal insufficiency (%) | 19 | 24 | 0.75 |
Coronary artery disease (%) | 15 | 24 | 0.52 |
Diabetes mellitus (%) | 27 | 38 | 0.41 |
Hematologic malignancy (%) | 14 | 14 | 1.00 |
Neutropenia (%) | 14 | 14 | 1.00 |
Solid tumor (%) | 20 | 19 | 1.00 |
Solid organ transplant (%) | 7 | 21 | 0.04 |
Device use | |||
Central venous catheter (%) | 54 | 76 | 0.12 |
Foley catheter (%) | 37 | 71 | 0.01 |
Antibiotic use | |||
Prior antibiotics (%) | 69 | 80 | 0.80 |
Prior carbapenem use (%) | 22 | 59 | 0.01 |
Length of stay | |||
Mean days (range) | 23 (1–127) | 44 (4–223) | 0.02 |