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Table 2 Effects of shiikuwasha or grape extract supplementation on dexamethasone-induced changes

From: Dietary supplementation with shiikuwasha extract attenuates dexamethasone-induced skeletal muscle atrophy in aged rats

 

CTL

DEX

DEX + SE

DEX + GE

Body weight (g)

 Before DEX treatment

766.5 ± 32.8

757.6 ± 25.1

757.2 ± 20.5

777.0 ± 46.1

 After DEX treatment

735.0 ± 31.9

638.5 ± 20.1*

654.5 ± 19.8

663.5 ± 37.6

Body weight loss (g)

31.57 ± 2.84

119.06 ± 8.68*

102.74 ± 10.66

113.58 ± 10.68

Average dietary intake (g)

 7 days before DEX treatment

22.4 ± 0.30

21.6 ± 0.72

19.4 ± 1.01

20.94 ± 0.51

 5 days during DEX treatment

13.1 ± 0.14

11.52 ± 0.91

9.33 ± 0.86

11.14 ± 1.12

Serum insulin (ng/ml)

0.56 ± 0.13

12.03 ± 2.54*

8.42 ± 1.42

14.06 ± 2.98

  1. Values are mean ± SEM (n = 5 or 6)
  2. CTL control group, DEX dexamethasone treatment group, DEX + SE dexamethasone treatment and shiikuwasha extract supplemented group, DEX + GE dexamethasone treatment and grape extract supplemented group
  3. P < 0.05 CTL versus DEX (student t-test)