From: Effect of cobalt(II) chloride hexahydrate on some human cancer cell lines

Concentration of CoCl_{2}·6H_{2}O (mg/L) (x)
| ||||||||
---|---|---|---|---|---|---|---|---|

Cell line | Inhibition (%) (y) | Regression equation |
IC_{50}
| |||||

5 | 10 | 25 | 50 | 75 | 100 | |||

293 T | 7.27 | 16.97 | 27.73 | 47.26 | 62.67 | 69.72 |
y = 20.92 ln(x) − 31.03 R = 0.977*** | 48.1 |

IMR-32 | 31.24 | 66.60 | 77.22 | 78.10 | 79.01 | 79.22 |
y = 13.59 ln(x) + 23.33 R = 0.849*** | 7.12 |

PC-3 | 19.80 | 31.58 | 49.70 | 67.98 | 80.36 | 82.08 |
y = 21.86 ln(x) − 17.49 R = 0.995*** | 21.91 |

A549 | 0.817 | 5.48 | 46.92 | 73.61 | 80.02 | 80.79 |
y = 30.61 ln(x) − 53.93 R = 0.980*** | 29.81 |

Two-way ANOVA summary table | ||||||
---|---|---|---|---|---|---|

Source of variation | df | SS | MSS | F-ratio |
Tukey’s HSD_{0.05}
| 4.79 |

Treatment (cell line) | 3 | 8632.36 | 2877.45 | 470.06*** | ||

Dose (CoCl_{2}·6H_{2}O)
| 5 | 39,715.85 | 7943.17 | 1297.59*** | ||

Treatment × dose (interaction) | 15 | 5669.54 | 377.97 | 61.75*** | ||

Error | 48 | 293.83 | 6.12 | |||

Total | 71 | 54,311.57 |