Table 3 Time to onset of reaction and symptoms
Variables | Moderate (n = 33) | Severe (n = 37) | p |
|---|---|---|---|
Time to onset (min) | 7.0 (4.0–19.5) | 4.0 (2.5–5.0) | <0.001 |
Time to onset | 0.008 | ||
<1 h (immediate) | 27 (81.8) | 37 (100.0) | |
>1 h (delayed) | 6 (18.2) | 0 | |
Symptoms | |||
Skin/mucosal | 26 (78.8) | 32 (86.5) | 0.394 |
Urticaria | 24 | 26 | |
Angioedema | 21 | 16 | |
Respiratory | 19 (57.6) | 16 (43.2) | 0.231 |
Dyspnea | 12 | 14 | |
Neck tightness | 6 | 2 | |
Stridor, hoarseness | 3 | 1 | |
Hypoxia | 0 | 1 | |
Central nervous system | 9 (27.3) | 25 (67.6) | 0.001 |
Faint/dizziness | 7 | 18 | |
Loss of consciousness | 2 | 9 | |
Seizure | 0 | 4 | |
Headache | 0 | 1 | |
Cardiovascular | 8 (24.2) | 36 (97.3) | <0.001 |
Hypotension | 0 | 36 | |
Chest discomfort | 7 | 4 | |
Tachycardia | 1 | 1 | |
Gastrointestinal | 4 (12.1) | 10 (27.0) | 0.120 |
Vomiting | 3 | 8 | |
Abdominal pain | 1 | 4 | |
Diarrhea | 0 | 0 | |