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Fig. 2 | SpringerPlus

Fig. 2

From: A systematic review of association studies of common variants associated with idiopathic congenital talipes equinovarus (ICTEV) in humans in the past 30 years

Fig. 2

Genetic study history of ICTEV is shown. Different genes were identified in different years which are listed in blue boxes. The genetic theories to explain the etiology of ICTEV are marked in the green boxes. Several genes were identified and verified by Professor Jacqueline T. Hecht and her research group (under the timeline on the left); they identified and verified several genes in addition to caspase pathway changes in ICTEV patients. Dr. Christina A Gurnett (under on the timeline on the right) first used second generation sequencing methods to study ICTEV. Professor Chun-Lian Jin (above the timeline) pioneered clubfoot genetic study among Chinese patients

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