Table 4 Comparative analysis of toxicity: original drug versus generic no. 2
From: Toxicities of docetaxel: original drug versus generics—a comparative study about 81 cases
Original drug (n = 38) | Generic no. 2 (n = 17) | p | |
|---|---|---|---|
Hypersensitivity | 1 (2.6 %) | 0 (0 %) | 1 |
Peripheral sensory neuropathy | 2 (5.3 %) | 2 (11.8 %) | 0.58 |
Hematological toxicities | 5 (13.2 %) | 4 (23.5 %) | 0.43 |
Febrile neutropenia | 1 (2.6 %) | 1 (5.9 %) | 0.52 |
Gastrointestinal toxicity | 2 (5.3 %) | 3 (17.6 %) | 0.16 |
Skin toxicity | 0 (0 %) | 3 (17.6 %) | 0.026 |
Hand foot syndrome grade III | 0 (0 %) | 2 (11.8 %) | 0.09 |
Ichthyosis-like eruption | 0 (0 %) | 1 (5.9 %) | 0.3 |
Treatment discontinuation | 3 (7.9 %) | 5 (29.4 %) | 0.09 |