Table 3 Comparative analysis of toxicity: original drug versus generic no. 1
From: Toxicities of docetaxel: original drug versus generics—a comparative study about 81 cases
Original drug (n = 38) | Generic no. 1 (n = 15) | p | |
|---|---|---|---|
Hypersensitivity | 1 (2.6 %) | 0 (0 %) | 1 |
Peripheral sensory neuropathy | 2 (5.3 %) | 2 (13.3 %) | 0.56 |
Hematological toxicities | 5 (13.2 %) | 3 (20 %) | 0.67 |
Febrile neutropenia | 1 (2.6 %) | 1 (6.7 %) | 0.49 |
Gastrointestinal toxicity | 2 (5.3 %) | 2 (13.3 %) | 0.56 |
Skin toxicity (hand foot syndrome grade III) | 0 (0 %) | 1 (6.7 %) | 0.28 |
Treatment discontinuation | 3 (7.9 %) | 4 (26.7 %) | 0.09 |