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Table 2 Binding constants, binding-site numbers and relative thermodynamic parameters of TC and its degradation products with BSA

From: Insights into the interactions between tetracycline, its degradation products and bovine serum albumin

Drug Temperature (K) KA (L mol−1) n R2 G (KJ mol−1) H (KJ mol−1) S (J mol−1 K−1)
TC 293 5.13 × 104 1.01 0.996 −26.40 −19.41 23.86
  298 4.50 × 104 1.17 0.997 −26.52
  304 3.60 × 104 1.17 0.999 −26.66
  310 3.39 × 104 1.18 0.999 −26.81
ATC 293 1.87 × 105 1.07 0.999 −29.40 −15.10 48.80
  298 1.45 × 105 1.18 0.998 −29.64
  304 1.36 × 105 1.09 0.998 −29.94
  310 1.30 × 105 1.08 0.999 −30.23
ETC 293 2.95 × 104 1.00 0.998 −24.96 −12.12 43.81
  298 2.44 × 104 1.05 0.999 −25.18
  304 2.30 × 104 1.12 0.999 25.44
  310 2.21 × 104 1.17 0.995 −25.70