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Table 5 Summary of impact analysis of % drug loading on different formulation parameters of formulations F1–F5 using simple linear regression model (level of significance 0.05)

From: Design, characterization and in vitro evaluation of HPMC K100 M CR loaded Fexofenadine HCl microspheres

Formulation parameters

Regression coefficient (β)

P value

Result

Comment

Yield (%)

0.04153

0.10648

P value >0.05

Statistically insignificant

Drug entrapment efficiency (%)

0.037828

0.000848

P value <0.05

Statistically significant

Time required for 50 % of drug release (T50%)

0.0032752

0.000314

P value <0.05

Statistically significant