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Table 5 Summary of impact analysis of % drug loading on different formulation parameters of formulations F1–F5 using simple linear regression model (level of significance 0.05)

From: Design, characterization and in vitro evaluation of HPMC K100 M CR loaded Fexofenadine HCl microspheres

Formulation parameters Regression coefficient (β) P value Result Comment
Yield (%) 0.04153 0.10648 P value >0.05 Statistically insignificant
Drug entrapment efficiency (%) 0.037828 0.000848 P value <0.05 Statistically significant
Time required for 50 % of drug release (T50%) 0.0032752 0.000314 P value <0.05 Statistically significant