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Table 4 The best fitted model and mechanism of drug release from F1, F2, F3, F4 and F5

From: Design, characterization and in vitro evaluation of HPMC K100 M CR loaded Fexofenadine HCl microspheres

Formulation

Best fitted model

n value

Release mechanism

F1

First order, Higuchi, Korsmeyer–Peppas and Hixson–Crowell

0.403

Fickian transport

F2

First order, Higuchi, Korsmeyer–Peppas and Hixson–Crowell

0.406

Fickian transport

F3

First order, Higuchi, Korsmeyer–Peppas and Hixson–Crowell

0.428

Fickian transport

F4

Higuchi, Korsmeyer–Peppas and Hixson–Crowell

0.453

Non-Fickian/anomalous transport

F5

Higuchi, Korsmeyer–Peppas and Hixson–Crowell

0.462

Non-Fickian/anomalous transport