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Table 4 The best fitted model and mechanism of drug release from F1, F2, F3, F4 and F5

From: Design, characterization and in vitro evaluation of HPMC K100 M CR loaded Fexofenadine HCl microspheres

Formulation Best fitted model n value Release mechanism
F1 First order, Higuchi, Korsmeyer–Peppas and Hixson–Crowell 0.403 Fickian transport
F2 First order, Higuchi, Korsmeyer–Peppas and Hixson–Crowell 0.406 Fickian transport
F3 First order, Higuchi, Korsmeyer–Peppas and Hixson–Crowell 0.428 Fickian transport
F4 Higuchi, Korsmeyer–Peppas and Hixson–Crowell 0.453 Non-Fickian/anomalous transport
F5 Higuchi, Korsmeyer–Peppas and Hixson–Crowell 0.462 Non-Fickian/anomalous transport