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Table 3 Release rate constants and R2 values for different release kinetics of five formulations (F1, F2, F3, F4 and F5) of Fexofenadine HCl microspheres

From: Design, characterization and in vitro evaluation of HPMC K100 M CR loaded Fexofenadine HCl microspheres

Formulation Zero order First order Higuchi Korsmeyer–Peppas Hixson–Crowell
K0 R2 K1 R2 KH R2 n KKP R2 KHC R2
F1 7.378 0.920 −0.187 0.983 26.48 0.991 0.403 0.33 0.975 0.206 0.981
F2 7.236 0.927 −0.177 0.974 25.86 0.989 0.406 0.32 0.976 0.197 0.979
F3 7.247 0.934 −0.173 0.973 25.84 0.992 0.428 0.30 0.983 0.194 0.980
F4 7.272 0.946 −0.168 0.968 25.77 0.991 0.453 0.28 0.986 0.191 0.980
F5 7.204 0.948 −0.161 0.964 25.46 0.990 0.462 0.27 0.985 0.187 0.978