Leptin levels after subarachnoid haemorrhage are gender dependent

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Table 3 Patients with severe organ failure (SOFA ≥ 3) in different organ systems

Time interval	Respiration			Cardiovascular			Haematology	Hepatic	Renal
Time interval	Female n (%)	Male n (%)	Sig.	Female n (%)	Male n (%)	Sig.	Female/male n (%)	Female/male n (%)	Female/male n (%)
0–48	15/39 (38)	5/17 (29)	ns	22/39 (56)	11/17 (65)	ns	0	0	0
49–96	17/38 (45)	7/17 (41)	ns	10/38 (26)	0	p < 0.0001	0	0	0
97–144	15/38 (39)	7/16 (44)	ns	6/38 (16)	0	p < 0.0001	0	0	0
145–192	14/35 (40)	16/6 (38)	ns	1/35 (3)	0	ns	0	0	0
193–240	7/35 (20)	5/16 (31)	ns	1/35 (3)	0	ns	0	0	0

n = number of patients
ns = non-significant
s = significant difference p < 0.05
Leptin values in patients with a severe organ failure defined as SOFA ≥ 3 in at least one organ system at any time during the study period
Sequential Organ Failure Assessment (SOFA) scores organ failure from zero; no organ failure, to four; pronounced organ failure. Six different organ systems are scored; respiration, haematology, hepatic, cardiovascular, renal and central nervous system (CNS). The worst value obtained during a 24-h period is used. In this study the SOFA CNS score was not used