The choice of multi-beam IMRT for whole breast radiotherapy in early-stage right breast cancer

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Table 4 Estimated p-values for compared treatment modalities for heart, LAD and contralateral breast

Metric	A versus B	A versus C	A versus D	A versus E	B versus C	B versus D	B versus E	C versus D	C versus E	D versus E
Heart (RB)
D_max	NS	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	NS	0.007	0.013
D_mean	NS	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	0.002	NS	0.007
V₅ (%)	NS	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	NS	NS	NS
V10 (%)	NS	<0.001	NS	0.030	<0.001	NS	0.030	NS	NS	NS
LAD (RB)
Dmax	NS	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	NS	0.002	0.016
Dmean	NS	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	0.022	0.026	NS
CB (RB)
V₃ (%)	NS	<0.001	<0.001	0.006	<0.001	<0.001	0.006	0.001	NS	<0.001
V₅ (%)	NS	NS	<0.001	NS	NS	<0.001	NS	0.003	NS	<0.001

A, three-dimensional conformal radiotherapy (3DCRT); B, forward-planned intensity-modulated radiotherapy (for-IMRT); C, inverse-planned intensity-modulated radiotherapy (inv-IMRT); D, helical tomotherapy (HT) and E, volumetric-modulated arc therapy (VMAT); RB, right breast, CB, contralateral breast and NS, no significant statistical differences