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Table 1 51 Reported cases of MAHA associated with breast cancer

From: Microangiopathic hemolytic anemia associated with metastatic breast cancer: case report and literature review

Author

Age

Bone marrow metastasis

Intervention

Prognosis (survival time)

Notes

Pendse et al. (2014)

69

+

None

Soon death

 

Kok et al. (2014)

43

Bone meta only

Discontinuation of GEM

Recovery

s/o GEM induced MAHA

Lechner and Obermeier (2012) (case reports review included 36 breast cancer cases)

Average 54 (19–82)

24/36

Each cases

4 months (chemotherapy)

Half a month (no treatment)

 

George (2011)

52

+

Plasma exchange

3 days

Death due to micro thrombi in multiple organs

Himmelmann and Schefer (2009)

66

–

None

10 days

 

Lockhart (2001)

Unknown (middle age)

+

Chemotherapy

Survival for more than 1 year

 

Fontana et al. (2001) (Case A)

69

+

Chemotherapy

No description of death

 

Fontana et al. (2001) (Case B)

62

+

None

4 days

 

Fontana et al. (2001) (Case C)

60

+

None

1 day

Death due to pulmonary embolism

Ataga and Graham (1999)

46

+

None

7 days

 

Narita et al. (1997)

45

+

Chemoendcrinetherapy

No description of death

 

Nordstrom and Strang (1993)

58

+

Chemotherapy

12 months

 

Bastecky et al. (1992)

28

+

None

10 days

Death due to pulmonary embolism

Collins et al. (1991)

54

+

Chemotherapy and plasma exchange

No description of death

 

N Engl J Med Case Record. (1984)

53

Unknown

Plasma exchange

4 days

Death due to tumor embolism in liver

Own case 2015

54

−

Chemotherapy

13 months

 
  1. The literature was extracted from 1984 to 2015
  2. GEM gemcitabine