|
Inheritance
|
No definite pattern
|
X-linked recessive
|
Sporadic
|
|
Age of presentation
|
Puberty
|
Congenital
|
First year of life
|
|
Natural History
|
Progressive
|
Non-progressive
|
Progressive
|
|
Symptoms
|
Frequent change of glasses
|
Variable and nonspecific
|
Watering, photophobia
|
|
Intra ocular pressure (IOP)
|
Normal
|
Normal
|
Elevated
|
|
Corneal diameter
|
>13mm; symmetric with increased WTW diameter
|
>13mm; symmetric
|
Variable, depends upon severity of glaucoma
|
|
Axial length
|
Increased axial length
|
Normal
|
Increased axial length
|
|
Iris
|
Iridodonesis ±
|
Iridodonesis; iris stromal hypoplasia
|
Normal with high insertion
|
|
Optic disc
|
Usually normal
|
Normal with increased propensity for glaucoma
|
Cup:disc ratio increased
|
|
Treatment
|
Refractive error correction and keratoplasty in advanced cases
|
Refractive errors correction
|
Control of IOP (medically/surgically)
|
